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| Cat.No | ACP13794 | Target Name | TRMT2B |
|---|---|---|---|
| Target Synonyms | TRMT2B; CXorf34; tRNA; uracil(54)-C(5))-methyltransferase homolog; EC 2.1.1.35; TRM2 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-504 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96GJ1 |
|---|
Uniprot Id
Q96GJ1
Target Species
Human
Target Name
TRMT2B
Target Full Name
tRNA (uracil-5-)-methyltransferase homolog B
Target Function
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, RNA M5U methyltransferase family
Target Synonyms
TRMT2B; CXorf34; tRNA; uracil(54)-C(5))-methyltransferase homolog; EC 2.1.1.35; TRM2 homolog
Target Background
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.
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