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| Cat.No | ACP16244 | Target Name | TYW1B |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-668 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6NUM6 |
|---|
Uniprot Id
Q6NUM6
Target Species
Human
Target Name
TYW1B
Target Full Name
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B
Target Function
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.
Target Protein Families
TYW1 family
Target Synonyms
TYW1B; RSAFD2; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B; EC 4.1.3.44; Radical S-adenosyl methionine and flavodoxin domain-containing protein 2; tRNA wybutosine-synthesizing protein 1 homolog B
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