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Recombinant Human Tropomodulin-2 (TMOD2)

ACP10864

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10864 Target NameTMOD2
Target SynonymsTMOD2; NTMOD; Tropomodulin-2; Neuronal tropomodulin; N-TmodFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-351
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NZR1
Background Information
  • Uniprot Id

    Q9NZR1

  • Target Species

    Human

  • Target Name

    TMOD2

  • Target Full Name

    Tropomodulin-2

  • Target Function

    Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton.

  • Target Protein Families

    Tropomodulin family

  • Target Tissue Specificity

    Neuronal-tissue specific.

  • Target Synonyms

    TMOD2; NTMOD; Tropomodulin-2; Neuronal tropomodulin; N-Tmod

  • Target Background

    This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.

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