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| Cat.No | ACP15098 | Target Name | TP53INP2 |
|---|---|---|---|
| Target Synonyms | C20orf110; Diabetes and obesity regulated, p53 inducible protein U; DOR; p53-inducible protein U; PIG-U; PINH; T53I2_HUMAN; Tp53inp2; Tumor protein p53-inducible nuclear protein 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-220 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IXH6 |
|---|
Uniprot Id
Q8IXH6
Target Species
Human
Target Name
TP53INP2
Target Full Name
Tumor protein p53-inducible nuclear protein 2
Target Function
Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.
Target Synonyms
C20orf110; Diabetes and obesity regulated, p53 inducible protein U; DOR; p53-inducible protein U; PIG-U; PINH; T53I2_HUMAN; Tp53inp2; Tumor protein p53-inducible nuclear protein 2
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