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Recombinant Human U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3)

ACP20958

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Specifications

Cat.No	ACP20958	Target Name	PRPF3
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-683	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O43395

Background Information

Uniprot Id

O43395
Target Species

Human
Target Name

PRPF3
Target Full Name

U4/U6 small nuclear ribonucleoprotein Prp3
Target Function

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
Target Involvement

Retinitis pigmentosa 18 (RP18)
Target Subcellular Location

Nucleus. Nucleus speckle.
Target Tissue Specificity

Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain.
Target Synonyms

hPrp3; HPRP3P; Pre mRNA splicing factor 3; Pre-mRNA-splicing factor 3; Precursor mRNA-processing factor 3; S. crevisiae; homolog of; PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae); Prp3p; PRPF3; PRPF3_HUMAN; RP18; SNRNP90; U4/U6 small nuclear ribonucleoprotein PRP3; U4/U6 snRNP 90 kDa protein
Target Background

The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.

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Recombinant Human U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3)

Specifications

Immunogen Information

Inquire Recombinant Human U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3) Now

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