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| Cat.No | ACP04077 | Target Name | LSM10 |
|---|---|---|---|
| Target Synonyms | LSM10U7 snRNA-associated Sm-like protein LSm10 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-123aa |
| Mol Weight | 30.1kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q969L4 |
|---|
Uniprot Id
Q969L4
Target Species
Human
Target Name
LSM10
Target Full Name
U7 snRNA-associated Sm-like protein LSm10
Target Function
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
Target Subcellular Location
Nucleus.
Target Protein Families
SnRNP Sm proteins family
Target Research Area
Transcription
Target Synonyms
LSM10U7 snRNA-associated Sm-like protein LSm10
Target Background
Enables U7 snRNA binding activity. Involved in positive regulation of G1/S transition of mitotic cell cycle. Located in Cajal body. Part of U7 snRNP.
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