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| Cat.No | ACP21849 | Target Name | USP27X |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-438 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A6NNY8 |
|---|
Uniprot Id
A6NNY8
Target Species
Human
Target Name
USP27X
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 27
Target Function
Deubiquitinase that can reduce the levels of BCL2L11/BIM ubiquitination and stabilize BCL2L11 in response to the RAF-MAPK-degradation signal. By acting on BCL2L11 levels, may counteract the anti-apoptotic effects of MAPK activity.
Target Involvement
Mental retardation, X-linked 105 (MRX105)
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
Peptidase C19 family
Target Synonyms
USP27X; USP22L; USP27; Ubiquitin carboxyl-terminal hydrolase 27; EC 3.4.19.12; Deubiquitinating enzyme 27; Ubiquitin carboxyl-terminal hydrolase 22-like; Ubiquitin thioesterase 27; Ubiquitin-specific-processing protease 27; X-linked ubiquitin carboxyl-terminal hydrolase 27
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