Home Products Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47 (USP47), Truncated

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47 (USP47), Truncated

ACP12601

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Specifications

Cat.No	ACP12601	Target Name	USP47
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96K76

Background Information

Uniprot Id

Q96K76
Target Species

Human
Target Name

USP47
Target Full Name

Ubiquitin carboxyl-terminal hydrolase 47
Target Function

Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.
Target Subcellular Location

Cytoplasm.
Target Protein Families

Peptidase C19 family
Target Tissue Specificity

Expressed in skeletal muscle, heart and testis.
Target Synonyms

Deubiquitinating enzyme 47; TFRP; Trf TATA binding protein related factor proximal homolog; Trf TATA binding protein related factor proximal homolog Drosophila; Ubiquitin carboxyl-terminal hydrolase 47; Ubiquitin specific peptidase 47; Ubiquitin specific processing protease 47; Ubiquitin specific protease 47; Ubiquitin thioesterase 47; Ubiquitin thiolesterase 47; Ubiquitin-specific-processing protease 47; UBP47_HUMAN; USP47
Target Background

Enables WD40-repeat domain binding activity and thiol-dependent deubiquitinase. Involved in several processes, including monoubiquitinated protein deubiquitination; negative regulation of G2/M transition of mitotic cell cycle; and negative regulation of nitrogen compound metabolic process. Located in cytoplasm. Part of SCF ubiquitin ligase complex.

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Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47 (USP47), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47 (USP47), Truncated Now

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