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Recombinant Human UBX domain-containing protein 6 (UBXN6)

ACP11315

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11315 Target NameUBXN6
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-441Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BZV1
Background Information
  • Uniprot Id

    Q9BZV1

  • Target Species

    Human

  • Target Name

    UBXN6

  • Target Full Name

    UBX domain-containing protein 6

  • Target Function

    May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Early endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein.

  • Target Tissue Specificity

    Enhanced expression in testis.

  • Target Synonyms

    UBX domain containing 1; UBX domain containing 2; UBX domain containing protein 1; UBX domain containing protein 6; UBX domain protein 6; UBX domain-containing protein 1; UBX domain-containing protein 6; UBXD1; UBXDC2; Ubxn6; UBXN6_HUMAN

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