Recombinant Human UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2), Truncated

Uniprot Id

Q9NY97

Target Species

Human

Target Name

B3GNT2

Target Full Name

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

Target Function

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors. Probably constitutes the main polylactosamine synthase.

Target Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.

Target Protein Families

Glycosyltransferase 31 family

Target Tissue Specificity

Ubiquitous.

Target Synonyms

3-galactosyltransferase 7; 3-GalTase 7; 3-Gn-T1; 3-Gn-T2; 3-N-acetylglucosaminyltransferase 1; 3-N-acetylglucosaminyltransferase 2; b3Gal-T7; B3GN2_HUMAN; B3GNT; B3GNT2; Beta 1 3 galactosyltransferase 7; Beta-1; Beta-3-Gx-T7; Beta3Gal-T7; Beta3GalT7; Beta3Gn T1; Beta3Gn-T1; Beta3Gn-T2; Beta3GNT; BGnT-1; BGnT-2; UDP-Gal:beta-GlcNAc beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1; UDP-GlcNAc:betaGal beta-1

Target Background

This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene.