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Our Recombinant Human UAP1 protein is carefully designed for researchers working in the field of signal transduction. This full-length UDP-N-acetylhexosamine pyrophosphorylase (Antigen X; Sperm-associated antigen 2) is expressed in an E.coli system, spanning the 1-522aa expression region to provide the complete protein sequence. The UAP1 protein is N-terminal 6xHis-tagged, which simplifies purification and detection, ensuring consistent performance and reliable results in your experiments. With a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human UAP1 protein is available in both liquid and lyophilized powder forms. Trust in this high-quality protein to support your signal transduction research and provide dependable, reproducible outcomes.
Our Recombinant Human UAP1 protein is carefully designed for researchers working in the field of signal transduction. This full-length UDP-N-acetylhexosamine pyrophosphorylase (Antigen X; Sperm-associated antigen 2) is expressed in an E.coli system, spanning the 1-522aa expression region to provide the complete protein sequence. The UAP1 protein is N-terminal 6xHis-tagged, which simplifies purification and detection, ensuring consistent performance and reliable results in your experiments.
With a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human UAP1 protein is available in both liquid and lyophilized powder forms. Trust in this high-quality protein to support your signal transduction research and provide dependable, reproducible outcomes.
| Cat.No | ACP02382 | Target Name | UAP1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-522aa | Mol Weight | 62.8kDa |
| Protein Length | Full length | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16222 |
|---|
Uniprot Id
Q16222
Target Species
Human
Target Name
UAP1
Target Full Name
UDP-N-acetylhexosamine pyrophosphorylase
Target Function
Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
Target Subcellular Location
Cytoplasm. Note=In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
Target Protein Families
UDPGP type 1 family
Target Tissue Specificity
Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
Target Research Area
Signal Transduction
Target Synonyms
AGX 1; AGX; AGX-1; AGX-2; AGX1; Antigen X; AntigenX; SPAG 2; SPAG2; Sperm associated antigen 2; Sperm-associated antigen 2; UAP 1; uap1; UAP1_HUMAN; UDP N acetylhexosamine pyrophosphorylase; UDP N acteylglucosamine pyrophosphorylase 1; UDP-N-acetylglucosamine pyrophosphorylase
Target Background
Enables identical protein binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Located in cytosol; nucleoplasm; and plasma membrane.
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