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Recombinant Human Uncharacterized aarF domain-containing protein kinase 4 (ADCK4), Truncated

ACP07853

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP07853 Target NameCOQ8B
Target SynonymsCOQ8B; ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8BFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ96D53
Background Information
  • Uniprot Id

    Q96D53

  • Target Species

    Human

  • Target Name

    COQ8B

  • Target Full Name

    Atypical kinase COQ8B, mitochondrial

  • Target Function

    Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration.

  • Target Involvement

    Nephrotic syndrome 9 (NPHS9)

  • Target Subcellular Location

    Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.

  • Target Protein Families

    Protein kinase superfamily, ADCK protein kinase family

  • Target Tissue Specificity

    Widely expressed, including renal podocytes.

  • Target Synonyms

    COQ8B; ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B

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