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Recombinant Human Uncharacterized protein C16orf73 (C16orf73)

ACP13695

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Specifications

Cat.No	ACP13695	Target Name	MEIOB
Target Synonyms	MEIOB; C16orf73Meiosis-specific with OB domain-containing protein; EC 3.1.-.-	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-442
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8N635

Background Information

Uniprot Id

Q8N635
Target Species

Human
Target Name

MEIOB
Target Full Name

Meiosis-specific with OB domain-containing protein
Target Function

Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
Target Involvement

Spermatogenic failure 22 (SPGF22)
Target Subcellular Location

Cytoplasm. Nucleus. Chromosome.
Target Protein Families

MEIOB family
Target Tissue Specificity

In fetal gonads, specifically expressed in the ovary starting at the 14th weeks post fertilization. In the adult, restricted to testis.
Target Synonyms

MEIOB; C16orf73Meiosis-specific with OB domain-containing protein; EC 3.1.-.-

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Recombinant Human Uncharacterized protein C16orf73 (C16orf73)

Specifications

Immunogen Information

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