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| Cat.No | ACP16863 | Target Name | C9orf84 |
|---|---|---|---|
| Target Synonyms | SHOC1; C9orf84; Protein shortage in chiasmata 1 ortholog; EC 3.6.-.- | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5VXU9 |
|---|
Uniprot Id
Q5VXU9
Target Species
Human
Target Name
SHOC1
Target Full Name
Protein shortage in chiasmata 1 ortholog
Target Function
ATPase required during meiosis for the formation of crossover recombination intermediates. Binds DNA: preferentially binds to single-stranded DNA and DNA branched structures. Does not show nuclease activity in vitro, but shows ATPase activity, which is stimulated by the presence of single-stranded DNA. Plays a key role in homologous recombination and crossing-over in meiotic prophase I in male and female germ cells. Requiref for recruitment TEX11 and MSH4 to recombination intermediates.
Target Subcellular Location
Chromosome.
Target Synonyms
SHOC1; C9orf84; Protein shortage in chiasmata 1 ortholog; EC 3.6.-.-
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