Home Products Recombinant Human Uncharacterized protein KIAA0586 (KIAA0586), Truncated

Recombinant Human Uncharacterized protein KIAA0586 (KIAA0586), Truncated

ACP11348

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Specifications

Cat.No	ACP11348	Target Name	KIAA0586
Target Synonyms	KIAA0586; TALPID3; Protein TALPID3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BVV6

Background Information

Uniprot Id

Q9BVV6
Target Species

Human
Target Name

KIAA0586
Target Full Name

Protein TALPID3
Target Function

Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation. Involved in regulation of cell intracellular organization. Involved in regulation of cell polarity. Required for asymmetrical localization of CEP120 to daughter centrioles.
Target Involvement

Joubert syndrome 23 (JBTS23); Short-rib thoracic dysplasia 14 with polydactyly (SRTD14)
Target Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Photoreceptor inner segment. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
Target Protein Families

TALPID3 family
Target Tissue Specificity

Ubiquitously expressed. Expressed in photoreceptor cells (at protein level).
Target Synonyms

KIAA0586; TALPID3; Protein TALPID3

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Recombinant Human Uncharacterized protein KIAA0586 (KIAA0586), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Uncharacterized protein KIAA0586 (KIAA0586), Truncated Now

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