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| Cat.No | ACP05641 | Target Name | KIAA1024 |
|---|---|---|---|
| Target Synonyms | MINAR1; KIAA1024; UBTOR; Major intrinsically disordered Notch2-binding receptor 1; Membrane integral NOTCH2-associated receptor 1; Ubiquitination and mTOR signaling protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UPX6 |
|---|
Uniprot Id
Q9UPX6
Target Species
Human
Target Name
MINAR1
Target Full Name
Major intrinsically disordered Notch2-binding receptor 1
Target Function
Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR. Negatively regulates angiogenesis. Negatively regulates cell growth. Negatively regulates neurite outgrowth in hippocampal neurons.
Target Subcellular Location
Cell membrane; Single-pass type IV membrane protein.
Target Protein Families
UPF0258 family
Target Tissue Specificity
Widely expressed, including in breast epithelial cells and endothelial cells (at protein level). Expression is down-regulated in advanced breast tumors (at protein level).
Target Synonyms
MINAR1; KIAA1024; UBTOR; Major intrinsically disordered Notch2-binding receptor 1; Membrane integral NOTCH2-associated receptor 1; Ubiquitination and mTOR signaling protein
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