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| Cat.No | ACP16747 | Target Name | SDHAF4 |
|---|---|---|---|
| Target Synonyms | C6orf57; CF057_HUMAN; Chromosome 6 open reading frame 57; UPF0369 protein C6orf57 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 24-108 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5VUM1 |
|---|
Uniprot Id
Q5VUM1
Target Species
Human
Target Name
SDHAF4
Target Full Name
Succinate dehydrogenase assembly factor 4, mitochondrial
Target Function
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Binds to the flavoprotein subunit SDHA in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit SDHB into the SDH catalytic dimer.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
SDHAF4 family
Target Synonyms
C6orf57; CF057_HUMAN; Chromosome 6 open reading frame 57; UPF0369 protein C6orf57
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