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| Cat.No | ACP10410 | Target Name | RTFDC1 |
|---|---|---|---|
| Target Synonyms | RTF2; C20orf43; RTFDC1; AD-007; CDA05; HSPC164; HSPC169; Replication termination factor 2; RTF2; Replication termination factor 2 domain-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-306 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BY42 |
|---|
Uniprot Id
Q9BY42
Target Species
Human
Target Name
RTFDC1
Target Full Name
Replication termination factor 2
Target Function
Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA.
Target Subcellular Location
Chromosome.
Target Protein Families
Rtf2 family
Target Synonyms
RTF2; C20orf43; RTFDC1; AD-007; CDA05; HSPC164; HSPC169; Replication termination factor 2; RTF2; Replication termination factor 2 domain-containing protein 1
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