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| Cat.No | ACP11976 | Target Name | UBP1 |
|---|---|---|---|
| Target Synonyms | UBP1; LBP1; Upstream-binding protein 1; Transcription factor LBP-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-540 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NZI7 |
|---|
Uniprot Id
Q9NZI7
Target Species
Human
Target Name
UBP1
Target Full Name
Upstream-binding protein 1
Target Function
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
Target Subcellular Location
Nucleus.
Target Protein Families
Grh/CP2 family, CP2 subfamily
Target Tissue Specificity
Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines.
Target Synonyms
UBP1; LBP1; Upstream-binding protein 1; Transcription factor LBP-1
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