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Recombinant Human Upstream stimulatory factor 1 (USF1)

ACP24130

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP24130 Target NameUSF1
Target SynonymsUSF1; BHLHB11; USF; Upstream stimulatory factor 1; Class B basic helix-loop-helix protein 11; bHLHb11; Major late transcription factor 1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-310
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP22415
Background Information
  • Uniprot Id

    P22415

  • Target Species

    Human

  • Target Name

    USF1

  • Target Full Name

    Upstream stimulatory factor 1

  • Target Function

    Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.

  • Target Involvement

    Hyperlipidemia combined 1 (HYPLIP1)

  • Target Subcellular Location

    Nucleus.

  • Target Research Area

    Transcription

  • Target Synonyms

    USF1; BHLHB11; USF; Upstream stimulatory factor 1; Class B basic helix-loop-helix protein 11; bHLHb11; Major late transcription factor 1

  • Target Background

    This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.

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