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Recombinant Human Uracil nucleotide/cysteinyl leukotriene receptor (GPR17), Truncated

ACP08397

Number
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Specifications


Cat.No ACP08397 Target NameGPR17
Target SynonymsGPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ13304
Background Information
  • Uniprot Id

    Q13304

  • Target Species

    Human

  • Target Name

    GPR17

  • Target Full Name

    Uracil nucleotide/cysteinyl leukotriene receptor

  • Target Function

    Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.

  • Target Synonyms

    GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12

  • Target Background

    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to act upstream of or within negative regulation of inflammatory response to antigenic stimulus. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane.

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