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| Cat.No | ACP22392 | Target Name | UROD |
|---|---|---|---|
| Target Synonyms | DCUP_HUMAN; PCT; UPD; URO D; URO-D; urod; Uroporphyrinogen decarboxylase; Uroporphyrinogen III decarboxylase | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-367 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P06132 |
|---|
Uniprot Id
P06132
Target Species
Human
Target Name
UROD
Target Full Name
Uroporphyrinogen decarboxylase
Target Function
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Target Involvement
Familial porphyria cutanea tarda (FPCT); Hepatoerythropoietic porphyria (HEP)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Uroporphyrinogen decarboxylase family
Target Synonyms
DCUP_HUMAN; PCT; UPD; URO D; URO-D; urod; Uroporphyrinogen decarboxylase; Uroporphyrinogen III decarboxylase
Target Background
This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
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