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| Cat.No | ACP21164 | Target Name | USH2A |
|---|---|---|---|
| Target Synonyms | USH2A; Usherin; Usher syndrome type IIa protein; Usher syndrome type-2A protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75445 |
|---|
Uniprot Id
O75445
Target Species
Human
Target Name
USH2A
Target Full Name
Usherin
Target Function
Involved in hearing and vision as member of the USH2 complex. In the inner ear, required for the maintenance of the hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells. In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.
Target Involvement
Usher syndrome 2A (USH2A); Retinitis pigmentosa 39 (RP39)
Target Subcellular Location
Cell projection, stereocilium membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Target Tissue Specificity
Present in the basement membrane of many, but not all tissues. Expressed in retina, cochlea, small and large intestine, pancreas, bladder, prostate, esophagus, trachea, thymus, salivary glands, placenta, ovary, fallopian tube, uterus and testis. Absent in
Target Synonyms
USH2A; Usherin; Usher syndrome type IIa protein; Usher syndrome type-2A protein
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