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| Cat.No | ACP13853 | Target Name | USP6NL |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92738 |
|---|
Uniprot Id
Q92738
Target Species
Human
Target Name
USP6NL
Target Full Name
USP6 N-terminal-like protein
Target Function
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Target Subcellular Location
Golgi apparatus. Cytoplasmic vesicle.
Target Tissue Specificity
Widely expressed.
Target Synonyms
KIAA0019; Related to the N terminus of tre; Related to the N-terminus of tre; RN tre; RN-tre; RNTRE; TRE2NL; US6NL_HUMAN; USP6 N terminal like; USP6 N terminal like protein; USP6 N-terminal-like protein; USP6NL
Target Background
Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including plasma membrane to endosome transport; positive regulation of GTPase activity; and retrograde transport, plasma membrane to Golgi. Located in cytoplasmic vesicle and plasma membrane.
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