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| Cat.No | ACP13120 | Target Name | VPS8 |
|---|---|---|---|
| Target Synonyms | VPS8; KIAA0804; Vacuolar protein sorting-associated protein 8 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N3P4 |
|---|
Uniprot Id
Q8N3P4
Target Species
Human
Target Name
VPS8
Target Full Name
Vacuolar protein sorting-associated protein 8 homolog
Target Function
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Functions predominantly in APPL1-containing endosomes.
Target Subcellular Location
Early endosome.
Target Protein Families
VPS8 family
Target Synonyms
VPS8; KIAA0804; Vacuolar protein sorting-associated protein 8 homolog
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