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| Cat.No | ACP04590 | Target Name | BPHL |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | Yeast |
| Expression Range | 38-291aa | Mol Weight | 32.8 kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86WA6 |
|---|
Uniprot Id
Q86WA6
Target Species
Human
Target Name
BPHL
Target Full Name
Valacyclovir hydrolase
Target Function
Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
Target Protein Families
AB hydrolase superfamily, Lipase family
Target Tissue Specificity
Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle.
Target Research Area
Signal Transduction
Target Synonyms
Biphenyl hydrolase like ; Biphenyl hydrolase related ; biphenyl hydrolase-like (serine hydrolase); Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; Bphl; BPHL_HUMAN; Bphrp; Breast epithelial mucin associated antigen ; Breast epithelial mucin-associated antigen; MCNAA; Mucin-associated antigen; VACVase; Valacyclovir hydrolase; Valacyclovirase
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