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| Cat.No | ACP22281 | Target Name | VIP |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 81-122 | Protein Length | Cytoplasmic Domain |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P01282 |
|---|
Uniprot Id
P01282
Target Species
Human
Target Name
VIP
Target Full Name
VIP peptides
Target Function
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.; PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin.
Target Subcellular Location
Secreted.
Target Protein Families
Glucagon family
Target Synonyms
Peptide histidine methioninamide 27; Peptide histidine valine 42; PHM27; PHV42; Prepro VIP; Vasoactive intestinal peptide; Vasoactive intestinal polypeptide; VIP; VIP peptides; VIP peptides precursor; VIP_HUMAN
Target Background
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
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