Recombinant Human Voltage-dependent calcium channel gamma-1 subunit (CACNG1), Truncated

Uniprot Id

Q06432

Target Species

Human

Target Name

CACNG1

Target Full Name

Voltage-dependent calcium channel gamma-1 subunit

Target Function

Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.

Target Subcellular Location

Cell membrane, sarcolemma; Multi-pass membrane protein.

Target Protein Families

PMP-22/EMP/MP20 family, CACNG subfamily

Target Tissue Specificity

Skeletal muscle.

Target Research Area

Neuroscience

Target Synonyms

CACNG1; CACNLG; Voltage-dependent calcium channel gamma-1 subunit; Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma

Target Background

Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1, 4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs).