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| Cat.No | ACP02189 | Target Name | CACNG3 |
|---|---|---|---|
| Target Synonyms | Neuronal voltage-gated calcium channel gamma-3 subunit;Transmembrane AMPAR regulatory protein gamma-3;TARP gamma-3 | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-315aa |
| Mol Weight | 37.1 kDa | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60359 |
|---|
Uniprot Id
O60359
Target Species
Human
Target Name
CACNG3
Target Full Name
Voltage-dependent calcium channel gamma-3 subunit
Target Function
Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
PMP-22/EMP/MP20 family, CACNG subfamily
Target Research Area
Neuroscience
Target Synonyms
CACNG3; Voltage-dependent calcium channel gamma-3 subunit; Neuronal voltage-gated calcium channel gamma-3 subunit; Transmembrane AMPAR regulatory protein gamma-3; TARP gamma-3
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