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Recombinant Human Voltage-gated potassium channel subunit beta-3 (KCNAB3), Truncated

ACP21358

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21358 Target NameKCNAB3
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-404Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO43448
Background Information
  • Uniprot Id

    O43448

  • Target Species

    Human

  • Target Name

    KCNAB3

  • Target Full Name

    Voltage-gated potassium channel subunit beta-3

  • Target Function

    Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Shaker potassium channel beta subunit family

  • Target Tissue Specificity

    Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex, occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney, pancreas, placenta and skeletal muscle.

  • Target Synonyms

    AKR6A9 ; K; K(+) channel subunit beta-3; K+ channel beta 3 subunit; KCAB3_HUMAN; KCNA3.1B; KCNA3B ; KCNAB 3; Kcnab3; KV BETA 3; KV BETA3; Kv-beta-3; MGC116886 ; Voltage gated potassium channel subunit beta 3; Voltage-gated potassium channel subunit beta-3

  • Target Background

    This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit.

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