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| Cat.No | ACP09772 | Target Name | WASHC3 |
|---|---|---|---|
| Target Synonyms | WASHC3; AD-016; CCDC53; CGI-116; x0009; WASH complex subunit 3; Coiled-coil domain-containing protein 53 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-194 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y3C0 |
|---|
Uniprot Id
Q9Y3C0
Target Species
Human
Target Name
WASHC3
Target Full Name
WASH complex subunit 3
Target Function
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
Target Subcellular Location
Early endosome.
Target Protein Families
CCDC53 family
Target Synonyms
WASHC3; AD-016; CCDC53; CGI-116; x0009; WASH complex subunit 3; Coiled-coil domain-containing protein 53
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