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| Cat.No | ACP01588 | Target Name | WDFY1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-410aa | Mol Weight | 53.8 kDa |
| Protein Length | Full length | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IWB7 |
|---|
Uniprot Id
Q8IWB7
Target Species
Human
Target Name
WDFY1
Target Full Name
WD repeat and FYVE domain-containing protein 1
Target Function
Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.
Target Subcellular Location
Early endosome.
Target Research Area
Signal Transduction
Target Synonyms
FENS 1; FENS-1; FENS1; KIAA1435; Phosphoinositide binding protein 1; Phosphoinositide binding protein SR1; Phosphoinositide-binding protein 1; WD repeat and FYVE domain containing 1; WD repeat and FYVE domain-containing protein 1; WD40 and FYVE domain containing protein 1; WD40- and FYVE domain-containing protein 1; WDF1; WDFY1; WDFY1_HUMAN; ZFYVE17; Zinc finger FYVE domain containing protein 17; Zinc finger FYVE domain-containing protein 17
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