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| Cat.No | ACP19722 | Target Name | WDPCP |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-746 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95876 |
|---|
Uniprot Id
O95876
Target Species
Human
Target Name
WDPCP
Target Full Name
WD repeat-containing and planar cell polarity effector protein fritz homolog
Target Function
Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies.
Target Involvement
Bardet-Biedl syndrome 15 (BBS15); Congenital heart defects, hamartomas of tongue, and polysyndactyly (CHDTHP)
Target Subcellular Location
Cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
Target Protein Families
WD repeat fritz family
Target Synonyms
Bardet-Biedl syndrome 15 protein; Chromosome 2 open reading frame 86; DKFZp686C12204; Fritz; FRITZ_HUMAN; hFrtz; WD repeat containing protein C2orf86; WD repeat-containing and planar cell polarity effector protein; WD repeat-containing and planar cell polarity effector protein fritz homolog; WDPCP
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