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| Cat.No | ACP10300 | Target Name | WDR6 |
|---|---|---|---|
| Target Synonyms | WDR6; WD repeat-containing protein 6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NNW5 |
|---|
Uniprot Id
Q9NNW5
Target Species
Human
Target Name
WDR6
Target Full Name
tRNA (34-2'-O)-methyltransferase regulator WDR6
Target Function
Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
Target Subcellular Location
Cytoplasm. Note=Colocalizes in the cytoplasm with STK11/LKB1.
Target Protein Families
WD repeat WDR6 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
WDR6; WD repeat-containing protein 6
Target Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms.
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