Recombinant Human WW domain-binding protein 11 (WBP11)

Cat.No	ACP09638	Target Name	WBP11
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-641	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP09638

Target Name

WBP11

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-641

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9Y2W2

Background Information

Uniprot Id

Q9Y2W2
Target Species

Human
Target Name

WBP11
Target Full Name

WW domain-binding protein 11
Target Function

Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.
Target Subcellular Location

Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
Target Tissue Specificity

Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung.
Target Synonyms

DKFZp779M1063; MGC94547; Npw38 binding protein; Npw38 binding protein NpwBP; Npw38-binding protein; NpwBP; PPP1R165; Protein phosphatase 1 regulatory subunit 165; SH3 domain binding protein SNP70; SH3 domain-binding protein SNP70; SIPP1; SNP70; Splicing factor PQBP1 and PP1 interacting; Splicing factor that interacts with PQBP 1 and PP1; Splicing factor that interacts with PQBP-1 and PP1; WBP 11; WBP-11; Wbp11; WBP11_HUMAN; WW domain binding protein 11; WW domain-binding protein 11
Target Background

This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.

Recombinant Human WW domain-binding protein 11 (WBP11)

Specifications

Immunogen Information

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