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| Cat.No | ACP01486 | Target Name | XYLT2 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | Yeast |
| Expression Range | 37-865aa | Mol Weight | 93.9 kDa |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H1B5 |
|---|
Uniprot Id
Q9H1B5
Target Species
Human
Target Name
XYLT2
Target Full Name
Xylosyltransferase 2
Target Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.
Target Involvement
Spondyloocular syndrome (SOS); Pseudoxanthoma elasticum (PXE)
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.
Target Protein Families
Glycosyltransferase 14 family, XylT subfamily
Target Tissue Specificity
Widely expressed. Expressed at higher level in kidney and pancreas.
Target Research Area
Metabolism
Target Synonyms
Peptide O xylosyltransferase 1; Peptide O-xylosyltransferase 1; protein xylosyltransferase 2; PXYLT2; UDP-D-XYLOSE:PROTEOGLYCAN CORE PROTEIN BETA-D-XYLOSYLTRANSFERASE 2; UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase; XT II; XT-II; XT2; Xylosyltransferase 2; Xylosyltransferase II; xylT II; XylT-II; XYLT2; XYLT2_HUMAN
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