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| Cat.No | ACP12826 | Target Name | ZADH2 |
|---|---|---|---|
| Target Synonyms | ZADH2; PTGR3; Prostaglandin reductase 3; PRG-3; EC 1.3.1.48; Zinc-binding alcohol dehydrogenase domain-containing protein 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-377 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N4Q0 |
|---|
Uniprot Id
Q8N4Q0
Target Species
Human
Target Name
PTGR3
Target Full Name
Prostaglandin reductase 3
Target Function
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
Target Subcellular Location
Peroxisome.
Target Protein Families
Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
Target Synonyms
ZADH2; PTGR3; Prostaglandin reductase 3; PRG-3; EC 1.3.1.48; Zinc-binding alcohol dehydrogenase domain-containing protein 2
Target Background
Predicted to enable 13-prostaglandin reductase activity. Predicted to be involved in negative regulation of fat cell differentiation. Predicted to be located in peroxisome.
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