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| Cat.No | ACP16573 | Target Name | ZCCHC8 |
|---|---|---|---|
| Target Synonyms | DKFZp434E2220; ZCCHC8; ZCHC8_HUMAN; Zinc finger CCHC domain containing 8; Zinc finger CCHC domain containing protein 8; Zinc finger CCHC domain-containing protein 8 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-707 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6NZY4 |
|---|
Uniprot Id
Q6NZY4
Target Species
Human
Target Name
ZCCHC8
Target Full Name
Zinc finger CCHC domain-containing protein 8
Target Function
Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing. It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function.
Target Subcellular Location
Nucleus, nucleoplasm. Nucleus.
Target Protein Families
ZCCHC8 family
Target Synonyms
DKFZp434E2220; ZCCHC8; ZCHC8_HUMAN; Zinc finger CCHC domain containing 8; Zinc finger CCHC domain containing protein 8; Zinc finger CCHC domain-containing protein 8
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