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| Cat.No | ACP18895 | Target Name | ZNF224 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-707 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NZL3 |
|---|
Uniprot Id
Q9NZL3
Target Species
Human
Target Name
ZNF224
Target Full Name
Zinc finger protein 224
Target Function
May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Target Subcellular Location
Nucleus. Note=Colocalizes with DEPDC1A at the nucleus.
Target Protein Families
Krueppel C2H2-type zinc-finger protein family
Target Tissue Specificity
Ubiquitous. Mainly expressed in fetal tissues.
Target Synonyms
BMZF 2; BMZF-2; BMZF2; Bone marrow zinc finger 2; KOX22; Zinc finger 2; bone marrow; Zinc finger protein 224; Zinc finger protein 233; Zinc finger protein 255; Zinc finger protein 27 (KOX 22); Zinc finger protein 27; Zinc finger protein KOX22; Zinc finger protein ZNF255; ZN224_HUMAN; ZNF224; ZNF255; ZNF27
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