Recombinant Human Zinc finger protein 24 (ZNF24)

Uniprot Id

P17028

Target Species

Human

Target Name

ZNF24

Target Full Name

Zinc finger protein 24

Target Function

Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.

Target Subcellular Location

Nucleus.

Target Protein Families

Krueppel C2H2-type zinc-finger protein family

Target Tissue Specificity

Expressed in many tissues except in heart.

Target Synonyms

KOX17; Retinoic acid suppression protein A; RSG A; RSG-A; RSGA; Zfp191; Zinc finger and SCAN domain containing protein 3; Zinc finger and SCAN domain-containing protein 3; Zinc finger protein 191; Zinc finger protein 24; Zinc finger protein KOX17; ZNF 24; ZNF191; ZNF24; ZNF24_HUMAN; ZSCAN 3; ZSCAN3

Target Background

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.