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| Cat.No | ACP09922 | Target Name | IKZF2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-500 | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UKS7 |
|---|
Uniprot Id
Q9UKS7
Target Species
Human
Target Name
IKZF2
Target Full Name
Zinc finger protein Helios
Target Function
Associates with Ikaros at centromeric heterochromatin.
Target Subcellular Location
Nucleus.
Target Protein Families
Ikaros C2H2-type zinc-finger protein family
Target Synonyms
ANF1A2; HELIOS; IKAROS family zinc finger 2; Ikaros family zinc finger protein 2; IKZF 2; IKZF2; IKZF2_HUMAN; MGC34330; Zinc finger DNA binding protein Helios; Zinc finger protein Helios; Zinc finger protein subfamily 1A 2; ZNF1A2
Target Background
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
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