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| Cat.No | ACP14453 | Target Name | DPF1 |
|---|---|---|---|
| Target Synonyms | BAF45B; BRG1-associated factor 45B; D4; D4 zinc and double PHD fingers family 1; DPF1; DPF1_HUMAN; NEUD4; Neuro d4 homolog; Zinc and double PHD fingers family 1; Zinc finger protein neuro-d4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-380 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92782 |
|---|
Uniprot Id
Q92782
Target Species
Human
Target Name
DPF1
Target Full Name
Zinc finger protein neuro-d4
Target Function
May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Requiem/DPF family
Target Synonyms
BAF45B; BRG1-associated factor 45B; D4; D4 zinc and double PHD fingers family 1; DPF1; DPF1_HUMAN; NEUD4; Neuro d4 homolog; Zinc and double PHD fingers family 1; Zinc finger protein neuro-d4
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