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| Cat.No | ACP02820 | Target Name | MAP3K1 |
|---|---|---|---|
| Target Synonyms | Map3k1; Mekk; Mekk1; Mitogen-activated protein kinase kinase kinase 1; EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1216-1493aa |
| Mol Weight | 34.8kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P53349 |
|---|
Uniprot Id
P53349
Target Species
Mouse
Target Name
MAP3K1
Target Full Name
Mitogen-activated protein kinase kinase kinase 1
Target Function
Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
Target Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
Target Tissue Specificity
Highly expressed in the heart and spleen while a lower level expression is seen in the liver.
Target Research Area
Others
Target Synonyms
Map3k1; Mekk; Mekk1; Mitogen-activated protein kinase kinase kinase 1; EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1
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