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The antibody against Outer capsid glycoprotein VP7 was raised in rabbit using the Recombinant Rotavirus A Outer capsid glycoprotein VP7 protein (51-326AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Outer capsid glycoprotein VP7 was raised in rabbit using the Recombinant Rotavirus A Outer capsid glycoprotein VP7 protein (51-326AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-44596A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Outer capsid glycoprotein VP7 |
| Target Synonyms | antibody; Outer capsid glycoprotein VP7 antibody | Form | Liquid |
| Species Reactivity | Rotavirus A | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Rotavirus A Outer capsid glycoprotein VP7 protein (51-326AA) | Target Species | Rotavirus A |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P10501 |
Uniprot Id
P10501
Target Species
Rotavirus A
Target Function
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion. This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
Target Subcellular Location
Virion. Host endoplasmic reticulum lumen.
Target Protein Families
Rotavirus VP7 family
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