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The recombinant antibody against RPS19 was produced using a synthesized peptide derived from human RPS19 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, FC.
The recombinant antibody against RPS19 was produced using a synthesized peptide derived from human RPS19 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, FC.
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Western Blot | Positive WB detected in: HEK293 whole cell lysate, 293T whole cell lysate, K562 whole cell lysate, A549 whole cell lysate | All lanes: RPS19 antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 17 kDa | Observed band size: 15-20 kDa
| Cat.No | ADC-56684A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | RPS19 | Target Synonyms | 40S ribosomal protein S19 (Small ribosomal subunit protein eS19), RPS19 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, WB, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human RPS19 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P39019 |
Uniprot Id
P39019
Target Species
Human
Target Name
RPS19
Target Full Name
Small ribosomal subunit protein eS19
Target Function
Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
Target Involvement
Diamond-Blackfan anemia 1 (DBA1)
Target Subcellular Location
Nucleus. Note=Located more specifically in the nucleoli.
Target Protein Families
Eukaryotic ribosomal protein eS19 family
Target Tissue Specificity
Higher level expression is seen in the colon carcinoma tissue than normal colon tissue.
Target Synonyms
40S ribosomal protein S19; DBA; DBA1; HGNC:10402; Ribosomal protein S19; rps19; RS19_HUMAN; S19
Target Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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