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The antibody against PDS1 was raised in rabbit using the Recombinant Saccharomyces cerevisiae (Baker's yeast) PDS1 protein (240-369aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against PDS1 was raised in rabbit using the Recombinant Saccharomyces cerevisiae (Baker’s yeast) PDS1 protein (240-369aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: recombinant protein | All lanes: PDS1 Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 35 kDa | Observed band size: 35 kDa
| Cat.No | ADC-55297A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDS1 |
| Target Synonyms | Securin PDS1 YDR113C YD9727.08C | Form | Liquid |
| Species Reactivity | Saccharomyces cerevisiae (Baker's yeast) | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Immunogen Description | Recombinant Saccharomyces cerevisiae (Baker's yeast) PDS1 protein (240-369aa) | Target Species | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P40316 |
Uniprot Id
P40316
Target Species
Yeast
Target Name
PDS1
Target Function
Regulatory protein, which plays a central role in chromosome stability. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESP1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESP1.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Securin family
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