Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against vapC was raised in rabbit using the Recombinant Shigella flexneri vapC protein (1-132aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against vapC was raised in rabbit using the Recombinant Shigella flexneri vapC protein (1-132aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
Western Blot | Positive WB detected in: recombinant protein | All lanes: vapC Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 44 kDa | Observed band size: 44 kDa
| Cat.No | ADC-55326A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | vapC |
| Target Synonyms | tRNA(fMet)-specific endonuclease VapC (EC 3.1.-.-) (RNase VapC) (Toxin VapC) vapC mvpA stborf2 CP0245 | Form | Liquid |
| Species Reactivity | Shigella flexneri | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Immunogen Description | Recombinant Shigella flexneri vapC protein (1-132aa) | Target Species | Shigella flexneri |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O06662 |
Uniprot Id
O06662
Target Species
Shigella flexneri
Target Name
VAPC
Target Function
Toxic component of a type II toxin-antitoxin (TA) system. A tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Does not cleave tRNA(Met), tRNA(Arg2), tRNA(His), tRNA(Leu), tRNA(Phe) tRNA(Thr1), tRNA(Tyr) or tRNA(Val). Overexpression in E.coli inhibits translation, leads to loss of cell growth and degradation of tRNA(fMet); these effects are neutralized by expression of cognate antitoxin VapB. The VapB/VapC complex probably regulates transcription of its own promoter.; Ectopic overexpression in E.coli induces the YoeB toxin, but this is not the cause of VapC toxicity.
Target Protein Families
PINc/VapC protein family
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
