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The antibody against SNRNP70 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 201-300 of SNRNP70 (NP_003080.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SNRNP70 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 201-300 of SNRNP70 (NP_003080.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-15656A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SNRNP70 |
| Target Synonyms | RPU1; Snp1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 201-300 of SNRNP70 (NP_003080.2). | Immunogen Sequence | RGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERAR |
|---|---|---|---|
| Uniprot ID | P08621 |
Uniprot Id
P08621
Target Species
Human
Target Name
SNRNP70
Target Full Name
U1 small nuclear ribonucleoprotein 70 kDa
Target Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.
Target Subcellular Location
Nucleus speckle. Nucleus, nucleoplasm.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
SNRNP70; RNPU1Z; RPU1; SNRP70; U1AP1U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70
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