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The recombinant antibody against SOD1 was produced using the Recombinant Human SOD1 protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IF, FC.
The recombinant antibody against SOD1 was produced using the Recombinant Human SOD1 protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IF, FC.
$350.00
Immunofluorescence staining of Hela cell with SOD1 Recombinant Monoclonal Antibody at 1:20, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).
| Cat.No | ADC-56379A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | SOD1 | Form | Liquid |
| Species Reactivity | Human | Isotype | Mouse IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Affinity-chromatography purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, FC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human SOD1 protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P00441 |
Uniprot Id
P00441
Target Species
Human
Target Name
SOD1
Target Full Name
Superoxide dismutase [Cu-Zn]
Target Function
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Target Involvement
Amyotrophic lateral sclerosis 1 (ALS1)
Target Subcellular Location
Cytoplasm. Mitochondrion. Nucleus.
Target Protein Families
Cu-Zn superoxide dismutase family
Target Research Area
Metabolism
Target Synonyms
ALS; ALS1; Amyotrophic lateral sclerosis 1 adult; Cu/Zn SOD; Cu/Zn superoxide dismutase; Epididymis secretory protein Li 44; HEL S 44; Homodimer; hSod1; Indophenoloxidase A; IPOA; Mn superoxide dismutase; SOD; SOD soluble; SOD1; SOD2; SODC; SODC_HUMAN; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; Superoxide dismutase 1 soluble; Superoxide dismutase Cu Zn; Superoxide dismutase cystolic
Target Background
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
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