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The recombinant antibody against SOD2 was produced using a synthesized peptide derived from human SOD2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.
The recombinant antibody against SOD2 was produced using a synthesized peptide derived from human SOD2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.
$350.00
Western Blot | Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate, K562 whole cell lysate, Rat brain tissue, Brain tissue, Liver tissue | All lanes: SOD2 antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 25, 21, 19, 20 kDa | Observed band size: 25 kDa
| Cat.No | ADC-57024A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | SOD2 | Target Synonyms | mitochondrial (EC 1.15.1.1), SOD2, Superoxide dismutase [Mn] |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human SOD2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04179 |
Uniprot Id
P04179
Target Species
Human
Target Name
SOD2
Target Full Name
Superoxide dismutase [Mn], mitochondrial
Target Function
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Target Involvement
Microvascular complications of diabetes 6 (MVCD6)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Iron/manganese superoxide dismutase family
Target Synonyms
Indophenoloxidase B; IPO B; IPOB; Manganese containing superoxide dismutase; Manganese SOD; Manganese superoxide dismutase; Mangano superoxide dismutase; Mn SOD; Mn superoxide dismutase; MNSOD; MVCD6; SOD 2; SOD2; SODM_HUMAN; Superoxide dismutase [Mn] mitochondrial; Superoxide dismutase [Mn], mitochondrial; Superoxide dismutase 2 mitochondrial
Target Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
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